In the Dissertation on the basis of clinical, laboratory and statistical studies, the tone of the autonomic nervous system in goats and its role in lipid homeostasis is established. It has been determined that depending on the activity of the sympathetic and parasympathetic nervous system, changes in the blood content of fatty acids, cholesterol and lipoproteins of high, low and very low density occur. According to the results of the study, the differences between the coses of normothonics, vagotonics and sympathotonics were observed. Sympathator animals had high heart rate of 96,80±6.62, the intensity of the interval R-R 35,30±1.18 and small values of the interval R-R 0.63±0.04 (p≤0.05; p≤0.001). The goats of the vagoninics had opposite features, characterized by a decrease in the heart rate of 58,4±1.11, the intensity of the interval R-R 1.03,44±2.21 and the increase in the value of the interval R-R 12±0.04 (p≤0.01; p≤0.001). Normotonika animals, compared to other experimental groups, had average values. Taking into account the results of the goat, depending on the influence of the tone of the autonomic nervous system, have differences in the activity of the cardiovascular system. Due to this, their response to the stress factor will vary, which in turn will be reflected in productivity. It has been determined that the content of triacylglycerols in the blood serum of normothonics goats was the largest in comparison with the experimental group of sympathotonics (P<0.05) and vagonics (P<0.001). Low-density lipoproteins were found to be the lowest in normal-tonics compared to experimental animal groups of sympathotonites (P<0.05) and vagonics (P<0.01). It is determined that the content of high-density lipoproteins was the smallest in the goats of the experimental group of sympathotonics compared to such a research group of normotonics (P<0,001). It was found that the value of total cholesterol in the blood serum of normothonics was greater compared to the experimental group of sympathotonics (P<0.01) and less compared to the experimental group of animals of vagonics (P<0.01). The magnitude of the atherogenic index in the research group of normotonics was the lowest compared to the experimental group of sympathotonics (P<0.01) and animals of the experimental group of vagonics (P<0.05). It has been found that depending on the individual characteristics of the goat organism, which is reflected in the form of a sympatheticvagal balance, in which the influence of the sympathetic or parasympathetic nervous system prevails or the balanced interaction of the sympathetic and parasympathetic nervous system, the lipid metabolism processes differ. After static processing of saturated fatty acids, it is established: Fatty acid in animals with vagotonia, which is 1.01 ± 0.09, had the highest percentage content compared to normal (P<0.001). Capron acid in normotonics is 76% less than the percentage of sympathotonics and 54% less compared to vagotonics (P<0.05; P<0.001). Capric acid has the highest content in vagonics by 43% relative to normothonics (P<0.01). Lauric acid has the highest content in vagonics by 47% relative to normothonics (P<0.01). Myristic acid in normothonics is 18% less than the percentage of sympathotonics and 45% less than in vagotonics (P<0.05; P<0.001). Pentadecanoic acid in animals with normothonia is 40% higher than sympathotonics and 23% less than compared to vagonics (P<0.05; P<0.01). Palmitic acid has the highest content in vagonics by 6% relative to normothonics (P<0.01). Stearic acid in sympathotonics is 8% less than normal (P<0.001). Arachinic acid in sympathotonics is 28% higher than normal (P<0.01). Tricosanoic acid in animals with normothonia is 11% higher than sympathotonics and 12% more relative to vagonics (P<0.05; P<0.01). It is established that the tone of the autonomic nervous system has an effect on the content of saturated fatty acids in the blood plasma of goats. It has been determined that animals with the advantage of sympathetic nervous system have a lower content of saturated fatty acids in relation to other research groups. The experimental group of vagoninics have the highest content of saturated fatty acids in the blood plasma.