Ukrainian studies show high rates of depressive and anxiety symptoms, sleep disorders, signs of post-traumatic stress disorder and emotional burnout in volunteers. However, in the national scientific space there are practically no comprehensive clinical and psychopathological studies of this group, there is a lack of systematic assessment of socio-demographic and psychosocial predictors of the formation of neurotic and stress-associated mental disorders, as well as scientifically substantiated data on the effectiveness of medical and psychosocial programs specifically for volunteers in the conditions of the Russian-Ukrainian war. As a result of the study, it was found that socio-demographic and psychosocial characteristics have a statistically significant relationship (p<0.001) with the risk of developing neurotic and stress-associated disorders. Protective factors were female gender (OR=0.58), absence of children (OR=0.02), use of coping strategies: “physical activity” (OR=0.57), “walking in the fresh air” (OR=0.36), “hobbies/reading books” (OR=0.57), “breaks in study or work” (OR=0.47), and “tasty food” (OR=0.49). Predictors of the development of these disorders were being married (OR=40.00), "cold" relationships (OR=2.58), "bad" sleep (OR=9.09), "bad" nutrition (OR=4.40), "unsatisfactory" material and living conditions (OR=10.51), "dissatisfaction" with the choice of profession (OR=7.44), "difficult" adaptation to study/work (OR=40.72), increased level of constant stress during the last three months (OR=13.72), "unsatisfactory" assessment of one's own health (OR=11.31), and more frequent requests for help from mental health professionals during the war (OR=18.24). Volunteering parameters also had a statistically significant relationship with neurotic and stress-related disorders (p<0.001): participation in volunteering during the war (OR=33.29), emotional relief from volunteering (OR=7.36), activities in front-line areas or on the front line (OR=8.78), provision of services (OR=6.16) and assistance to military personnel (OR=3.97). The created system for predicting neurotic and stress-related disorders demonstrated high diagnostic efficiency (AUC=0.965) with a sensitivity of 0.917 and a specificity of 0.890 at a cut-off point of >15 points. A significantly higher effectiveness of the comprehensive program compared to pharmacotherapy was observed in reducing the levels of emotional manifestations in volunteers according to the HAM-D, HAM-A and HADS questionnaires, improving sleep quality indicators according to the PSQI, increasing quality of life indicators according to all scales of the MOS SF-36 questionnaire, reducing the level of general psychopathological symptoms according to the SCL-90-R, reducing the frequency and intensity of post-traumatic symptoms according to the SSS-PTSD and IES-R. The achieved positive changes were maintained three months after the start of the program, which indicated a prolonged effect.
