Zagajko A. Lipid transport system under oxydative stress in rats

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0400U000740

Thesis Registration Form

0400U000740.pdf

Applicant for

Specialization

  • 03.00.04 - Біохімія

01-03-2000

Specialized Academic Board

К 64.051.17

V.N. Karazin Kharkiv National University

Essay

Liver cytosole', blood' lipoproteins. Study the influence of oxidative stress on lipoprotein content and composition. Disk-electroforesis, turbidimetry, fermentative, colour methods were used. It was found that under oxidative stress the lipoprotein level in blood is increased and in in liver cytosole it is decreased in early times, and increased in next times. Under oxydative stress, which develops in presents of transcription and translation inhibitors there is less hyperlipoproteinemia. The atherogenic character of oxidative stress is manifestated in lipoprotein oxidation and in lipoprotein fraction redistribution with the increasing of atherogenic ones. Field of application ¦ scientific institutions of medical and biological type.

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