Yakymenko T. Neuroactive amino acids in genesis of seizury susceptibility of brain

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0400U000909

Thesis Registration Form

0400U000909.pdf

Applicant for

Specialization

  • 03.00.04 - Біохімія

15-03-2000

Specialized Academic Board

K 64.051.17

Essay

Object - Vistar line rat males with low and high levels of audiogenic excistability. Aim - establishment of neurotransmitter amino acid role and their functional interrelations in the process of formation of brain seizure susceptibility. Methods - biochemical, radioimmune, neurophysiological. The enterconnec- tion between interrelation particularities of excitining and inhibiting amino acid and the seizure threshold of brain structures of highlyexcitable rats was abtained. It has concluded that increaced contents of exciting amino acids and decreaced one of inhibitings is one of pathologic links of seizure susceptibility formation of brain. Field of application - scientific institutions of medical and biological type.

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