Vernygorods'kyj S. Morphogenesis of Fibrosing Alveolitis in Prolonged Use of Beta-adrenoblockers

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0401U003277

Thesis Registration Form

0401U003277.pdf

Applicant for

Specialization

  • 14.03.02 - Патологічна анатомія

06-12-2001

Specialized Academic Board

Д 26.003.06

Bogomolets National Medical University, Ministry of Health of Ukraine

Essay

Having studied the morphogenesis of propranolol fibrosing alveolitis stages in the dynamics of the disease have been discovered. Propranolol fibrosing alveolitis develops in three stages: sharp alveolitis, productive alveolitis, fibrosing alveolitis. The trigger mechanism of the alveolitis development is the damage of microcirculator channel vessels, type II pneumocytes and alveolar macrophages. The morphological changes have been positively confirmed by the biochemical findigs. In prolonged atenolol administration fibrosing alveolitis did not occur in the lungs experimental animals.

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