Zaritskaya M. The biochemical and structurally functional features of eruthron cell and platelets in insulin- dependent diabetes mellitus.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0402U002736

Thesis Registration Form

0402U002736.pdf

Applicant for

Specialization

  • 03.00.04 - Біохімія

23-09-2002

Specialized Academic Board

Д 26.240.01

Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine

Essay

Human and rat platelet suffering from healthy donors and IDDM patients. Biochemical processes of activation of platelets under the IDDM. Methods: immunocytochemistry and immunodetection with the monoclonal antibodies, Western blotting, electrophoresis. It is exhibited, that the high level of NO production in platelets under the IDDM is provided with activation of iNOS II. It is installed, that the activation of platelets. accompanies with the changes of their ultra structural organization. It was shown, that the ascending of aggregation of platelets under the IDDM is coupled to change of a ratio of cytoskeleton protein. Aria of application - scientific medical and biological institutions.

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Files

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