Fesenko S. Titrimetric determination of hydrophobic organic protolytes with the use aqueouse-micellar media of surfactants

The dissertation is devoted to the development of theoretical and practical approaches of the application of aqua?micellar solutions of surfactants for the determination of hydrophobic compounds by the titrimetric methods. It was shown the advisability of surfactants application for the determination of moderate organic protolytes. The distribution coefficient in water-octanole system was proposed as criterion of this advisability. It was discovered, investigated and used the differential influence of surfactants onto on protolytic properties of organic acids with different hydrophobity. On the basis of investigations it was proposed the procedures for the determination of main substance content in some pharmaceuticals and in their medicinal forms by the methods of acid-base, compleximetric and iodometric titrations.