Gritsenko P. Localization of polymerization sites in the fibrin D-domain and neoantigenic determinant inthe D-dimer of fibrin.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0403U002361

Thesis Registration Form

0403U002361.pdf

Applicant for

Specialization

  • 03.00.04 - Біохімія

23-06-2003

Specialized Academic Board

Д 26.240.01

Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine

Essay

The object of investigation is the fibrin and fibrin D- dimer. The aim is the search of the new polymerization sites in D-domain of human fibrin molecule and the localization of the neoantigenic determinant in fibrin D-dimer. It was shown that unknown sites taking participation into protofibril formation and protofibril lateral association are situated in the b- and g- polypeptide constituents of fibrin D-domain; neoantigenic determinant of D-dimer is localized in Bb1343-190 (most likely - in Bb155-160) fragment. Field of application: scientific and educational institutes of medical and biological type.

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Files

Avtoreferat_Gritsenko.doc

Thesis_Gritsenko.doc

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