AChKASOVA T. Immunity status and clinical characteristics of infectious mononucleosis in children.

The thesis concerns the immunity status and clinical characteristics of infectious mononucleosis in children. The basic clinical symptoms of the disease were defined; the degree of their intensity and duration of their manifestation was determined. The immunity status in children with infectious mononucleosis was examined. It was found that from the very first days of the disease the immunity gets inhibited, and this state persists during the clinical recovery period. According to the data obtained, a new approach to the treatment of infectious mononucleosis was suggested, which includes the immune correction therapy with cyclopheronum. The clinical and immunologic effectiveness of the drug was proved. For the first time the immunity state of children, who had infectious mononucleosis 1 year and 2 years ago, was studied. A year after the disease the detected immune disorders persist reliably; after 2 years the indices of cellular immunity get normalized while the state of nonspecific resistance remains reliably low. Children who had infectious mononucleosis need regular medical check-up for at least 2 years after the disease, including annual immunologic control and courses of immunity correction.