Malyuk M. Adaptation and compensation processes of cattle organism under influence excessive intake of nitrates depending on type of higher nervous activity (based on angiostomia data)

The object - adaptation and compensation process of heifers with different higher nervous activity types. The aim - to study metabolic process peculiarities of cattle (heifers) at nitrate stress influnce condition under industry conditions depending on type of higher nervous activity. The methods - out of chamber method for determination of higher nervous activity types, morphological, toxicological, biochemical. The novelty - for the first time in experiments on heifers with different higher nervous activity types conducted in industry conditions it were determined peculiarities of metabolic processes changes at excessive nitrates intake based on the results of blood samples examination which were taken from aorta and jugular vein at the same time. Formely unknown regularities of nitrates and nitrites accumulation and transformation have been determined under single excessive nitrates intake in animals with different individual properties of nervous processes. Under this condition obtained and scientifically grounded data on intensity of free radicals formation which has negative influence on metabolic processes, adaptation and compensation reactions and also changes activity of aspartate-aminotransferase, alanine- aminotransferase and sukcinatedehydragenase which regulate proteins and carbohydrates metabolism. It were determined and grounded the content changes of glucose, pyruvic acid, total protein, ammonia, glutamin, haemoglobin, methaemoglobin, free sulfhydril groups, seruloplasmin and three valency iron in transferine which appear at condition acute nitrate poisoning. These data give possibility to offer scientifically grounded principles of prevention and treatment of this animal toxication taking into account types of higher nervous activity. Field - veterinary medicine.