Yanchiy O. Comparative characteristic of the thiamine-binding proteins from the rat brain, liver and kidney

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0404U003431

Thesis Registration Form

0404U003431.pdf

Applicant for

Specialization

  • 03.00.04 - Біохімія

20-09-2004

Specialized Academic Board

Д 26.240.01

Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine

Essay

The object of investigation is thiamine-binding proteins. The aim is isolation, identification and comparative characterization of the thiamine-binding proteins from rat brain, liver and kidney. It is the first time the thiamine-binding proteins from rat liver and kidney have been isolated by methods of protein chemistry and compared to protein from rat brain, which was described earlier. It is found that these proteins do not differ by molecular weight, subunit structure and amino acid composition. The specific interaction between proteins and thiamine is shown; proteins also hydrolyze phosphoric esters of thiamine. These functions are universal for all tissues that are investigated. Field of application: scientific and educational institutions of biological profile.

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Files

referаt.doc

thesis.doc

Титульний лист.doc

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