Нufrij А. The activity of antioxidant defence system and enzymes of digestion in small intestine of steers under the stress action

The object of research - system of antioxidant defens of mucous membrane of intenstine and the activity of digestive enzymes of chyme of small intenstine and hormonal-metabolic profile of blood of young cattle at pharmacological and transport stress. Purpose of research - the activity of SOD, GPО and КТ in mucous membrane of smoll intenstine, amylase, proteinase, alkaline phosphatase in chyme of smoll intenstine, the concentration of hypophase, thyroid, pancretic, suprarenal gland and metabolites in blood. Methods of research: clinical - physiological, biochemical, hematological, radiometrical, mathematical. Science novelty: For the first it was studied the dynamics of enzyme САS activity in mucous membrane of small intenstine and functional state of glands of endocrine system of young cattle organism at different stage of the development of pharmacological and transport stress and by the injection of phenarole and aminazine to animals. It was fixed that the dependence of САS mucous memrane activityof small intenstine from the stage of development of pharmacological and transport stress and it was found out the of dinamic activity of enzymes САS of the same type by the stress action of different etbiology. The role of separate adaptive hormones of glands of internal secretion in forming of compensatory-adapted reaction of young cattle organism at different stage of realization the common adaptive syndrome was determined. For the prophylactic of technological stress in young cattle, for the first time, it was turned out comparatively new antioxidant phenarole together with aminazine and it was done scientifically - economical grouding of reasonability of their using. Level of introduction - on the base of received facts it was carried out and confirmed the Directive due to the complex using of preparation "Phenarole" and "Aminazine" at stress in bulls. For the warning of negative action of transport stress on the increment and health of young cattle we propose phenarole with combined feeds 1,25 mg/kg ofthe living mass daily during 12 days before using to feed and aminazine in form of 2,5 per cent of solution to inject on account of 0,5 mg/kg of the animal living mass once 60 minutes before transporting. Sphere of implementation - is veterinary medicine.