Prokopova K. Interferon-induced system of 2',5'-oligoadenylate in rat lymphoid cells under the conditions of irradiation

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U004628

Applicant for

Specialization

  • 03.00.04 - Біохімія

28-11-2005

Specialized Academic Board

Д 26.001.24

Taras Shevchenko National University of Kyiv

Essay

The key components of interferon-dependent 2',5'-oligoadenylate cascade in rat lymphoid cells under the irradiation in 0,25; 0,5; 0,75 and 1,0 Gy doses and participation of cyclic nucleotides and calcium ions in regulation of given cascade were investigated. Influence of interferon inducers and biologically active substance squalene upon the investigated indexes was studied under their use in vitro and in vivo for the purpose of radiation consequences correction.

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