Zadorozhna M. Role of alfa-2-antiplasmin in different stage of fibrinolytic process

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0406U002130

Thesis Registration Form

0406U002130.pdf

Applicant for

Specialization

  • 03.00.04 - Біохімія

22-05-2006

Specialized Academic Board

Д 26.240.01

Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine

Essay

The object of investigation is fibrinolytic process.The aim is investigation of role of alfa -2-antiplasmin in different stage of fibrinolytic process. Method of study: preparational biochemistry, enzymology, spectrophotometry, electrophoresis. Interaction alfa-2-antiplasmin with plasmin(ogen), fibrin(ogen) and tissue plasminogen activator was studied. It has been determinated that the alfa -2-antiplasmin inhibits of the Glu-plasminogen activation by tissue activator on fibrin. Purification of alfa -2-antiplasmin with high activity from human plasma was developed. Field of application: scientific and educational institutes of medical and biological type.

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Files

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