Nizhankovska O. Peroxide processes and the state of nitric oxide system in the vessel wall in the rats of different age

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0406U002193

Thesis Registration Form

0406U002193.pdf

Applicant for

Specialization

  • 03.00.04 - Біохімія

18-05-2006

Specialized Academic Board

Д 26.551.01

Essay

Investigation object: adult and old rats. Investigation purpose: comparative estimation of the processes state of lipid peroxidation, synthesis and level of oxide of nitrogen in the vascular wall of experimental animals of different age. Investigation methods: biochemical, statistic. Theoretical and practical results, novelty of the investigation: It is first set that peroxide transformation of polyunsaturated fatty acids tailings of phosphotides goes down with age, the level of the unsaturated fat acids goes down in the wall of aorta. With age in an aorta the products of NO (level of stable of metabolic) go down due to falling of cNO-synthase activity and arginase. Led to, that L-arginine with riboxine thus leading positive vasodilatory effect on a vascular wall mainly at old rats. Application: it is drawn on results in the scientific experiments. The field: biochemistry, pharmacology

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Files

aref.doc

Ніжанковська О.В. Вступ.doc

Ніжанковська О.В. Огляд1.doc

Ніжанковська О.В. Огляд2, методи дослідження.doc

Ніжанковська О.В. Розділ 3.doc

Ніжанковська О.В. Розділ 4.doc

Ніжанковська О.В. Розділ 5.doc

Ніжанковська О.В. Список літератури.doc

Ніжанковська О.В. Узагальнення результатів дослідження.doc

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