Filinska O. Biochemical mechanisms of membranotropic activity heteropolynuclear compounds

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0406U002649

Applicant for

Specialization

  • 03.00.04 - Біохімія

14-06-2006

Specialized Academic Board

Д 26.001.24

Taras Shevchenko National University of Kyiv

Essay

The dissertation is devoted to study of the biochemical features of action of the new synthesized heteropolynuclear compounds Cu2Co2(H2L)2(L)4 X2 (H2L, L=diethanolamine and its deprotonated residuum; X = Cl, Br, I, NCS, CH3СОO on lipid membrane matrix and activity of membrane binding enzymes of hepatocyte plasma membrane. It was established that interaction of heteropolynuclear compounds with artificial lipid membranes and biological membranes depends on an anion type.

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