Vadzyuk O. Kinetic regularity of the transport of Ca2+ in mitochondria of the myometrium and the influence of caffeine on this process.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0406U003677

Applicant for

Specialization

  • 03.00.04 - Біохімія

25-09-2006

Specialized Academic Board

Д 26.240.01

Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine

Essay

The object of investigation - mitochondria of the smooth muscle cells The aim: to investigate the kinetic properties of the transmembrane exchage of Ca2+ and the influence of caffeine on this process. Methods of study: prepаrative biochemistry, biochemical membranology, enzymology, spectrofotometry, spectrofluorimetry chemical and biochemical kinetics, statistic analisys. The kinetics of the Ca2+ accumulation has been studied in term of the rate constant. It has been shown, that caffeine modify transmembrane exchange of this process. New method of registration of ATP was developed. Results can be used in biochemical membranology. Field of application - research institution of biological and medical profile.

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