Dudka V. Morphoadaptive properties of bony tissue under one-sided menisusektomia

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0407U000061

Applicant for

Specialization

  • 16.00.02 - Патологія, онкологія і морфологія тварин

14-12-2006

Specialized Academic Board

Д 27.821.02

Essay

Object of investigation – subchondral epiphyseal and diaphyseal shin bone tissue of some mammals in normal form and with unilateral meniscectomy of dogs. The goat of investigation: to find out species-specific features of subchondral epiphyseal and diaphyseal bone tissue of animals with various support ways and morpho-functional adaptation after unilateral meniscectomy in dogs. The investigation method – anatomic, histological, histochemical, morphometric, radiological, electron –- microscopical, statistical. The scientific novelty: is, that research of the bone tissue structural organization of mammal shin together with setting of experiment on unilateral meniscectomy supplement existing data on this problem concerning adaptive plasticity of a bone tissue in view of changes of biodynamics in a joint. Specific features of subchondral bone tissue structure and compacts in different shin sites are found out in view of osteon and intermediate systems ratio. Some mechanisms of metabolic processes in a bonetissue after meniscectomy are being opened with the account of enzymatic activity alkaline phosphatase, the adaptation of dypherone cells of bone tissue is tracked at an ultrastructural level. Suggested: received data relative to morpho-functional adaptation of a bone tissue after unilateral meniscectomy to be used in regenerative and reconstructive surgery of locomotive device components. Materials of dissertational work can be used for writing relevant sections of textbooks on morphological disciplines, monographies, handbooks and also for research and study. Inculcated: results of dissertational work are used in educational process at The Bila Tserkva state agrarian university and research activity of 20 structural divisions of Ukraine higher educational institutions and research institutes, in the Russian Federation and Byelorussia Using area: veterinary medicine.

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