Dragan L. The involvement of proteinases and the system of poly-ADP-ribosylation in radiation-induced apoptosis of the rat thymus and spleen cells.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0407U001458

Applicant for

Specialization

  • 03.00.04 - Біохімія

26-03-2007

Specialized Academic Board

Д 26.001.24

Taras Shevchenko National University of Kyiv

Essay

The dissertation is devoted to the study of the involvement of proteinases and the system of poly-ADP-ribosylation in radiation-induced apoptosis of the rat thymus and spleen lymphoid cells. Increase in the level of DNA single- and double-strand breaks, as well as increase of the rate of Ca2+-, Mg2+-dependent polydeoxyribonucleotide accumulation, have been demonstrated. The injection of riboxine resulted in the normalization of investigated parameters.

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