Svyetlichna L. Pathomorphological changes in pigs infected by porcine parvovirus infection

The present thesis is devoted to a study of the pathomorphological changes of porcine parvovirus infections in different groups of swine. There were conducted the epizootologic inspections, studies of illness clinical signs, gross, histological and histochemical changes in different organs of stillborn piglets, dams, and in their placentes, infected with porcine parvovirus. The complex of pathognomonics for parvovirus infections of histologic changes in organs and tissues of stillborn pigs is established. It includes: a sludge-syndrome, raredfied location and destruction of lymphocytes in all immun organs and tissues, cataractous or haemorragic inflammation in a gastroenteric tract, serous-haemorragic hepatites, a granular dystrophy and destruction of excretion cells in a pancreas, serous inflammation and haemorragia in kidneys. In a heart one can find breaks of muscular fibres and granular dystrophy of cells. On lungs there are a growth and a hypostasis in a connecting tissue. In large bronchial tubes there are a growth of a connecting tissue and a destruction of cells in a muscular plate of a mucous membrane. In cerebral and a spinal cord there are parts of intensive infiltration of agrey substance by lymphocytes. Presence of a lot of intranuclear bodies-inclusions in cells of many organs and tissueses is a characterisric theacher especially in endotelyocites by vessels and in lymphocytes which represents virus, consisting of fiber and a nucleinic acid. Are suffed all the organs of stillborn pigs, infected by porcine parvovirus infection, infringement of an exchange of fibers, carbohydrates and nucleinic acids are registered. In the present thesis the tables containing results of morphometry researches of various organs and tissues of sows and deadborn pigs, infected by porcine parvovirus are presented.