Mazur O. Activity of enzymes of embryonic transplant energetic exchange

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U002298

Applicant for

Specialization

  • 03.00.04 - Біохімія

20-05-2008

Specialized Academic Board

Д 26.001.24

Taras Shevchenko National University of Kyiv

Essay

The experimental researches of energy and plastic metabolism of embryonic tissues and cells before and after allotransplantation to a mature organism are presented in the work. It was established on basis of received data that embryonic metabolism depends on the development of tissue, is characterized with high activity of energy metabolism. Embryonic tissues and cells are characterized with simultaneous existence and active functioning of embryonic type of metabolism and typical for mature organism metabolism. The activity of energy and plastic metabolism of transplanted embryonic tissues and cells does not depend on metabolic changes of environmental tissues of mature recipient. The morphologic transformation of embryonic transplants causes their transition to the type of metabolism, which is peculiar to mature organism. The method of duodenum stump peritonisation of human embryo peritoneum, on which it was taken out the patent to the invention under № 6755, 1994, was proposed to clinical application.

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