Bortnyak N. The state of regulative humoral substances in patients of different types of heart valve diseases in relationship to arterial hypertension

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0409U002212

Applicant for

Specialization

  • 14.01.12 - Ревматологія

16-04-2009

Specialized Academic Board

Д 26.003.08

Essay

The aim of investigation was to estimate changes of pressor and depressor humoral substances in develop mechanisms of arterial hypertension in patients with different types of heart valve diseases for optimising diagnostic and treatment efficacy. We evaluated 125 patients with valve heart diseases age from 19 to 65 yers. Among them 73 patients (58,4%) with valve heart diseases had arterial hypertension: essential hypertension was 30 pts, symptomatic - 43 pts. The levels of renin, angiotensin, aldosteron in blood plasma befor and after physical exersice in different types heart valve diseases were studied in connection with different forms of arterial hypertensions and chronic insufficient blood circulation. These risults were compared to the level of present figures of the patients suffering from heart valve disease and normal arterial blood pressure. The biggest changes were found in activity of renin-angiotensin-aldosteron system in pts with symptomatic arterial hypertension and in chronic rheumatic valve disease in active phase.

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