Klyuchka V. Diagnostic and treatment peculiarities of cerebral oligoastrocytomas.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0409U003020

Applicant for

Specialization

  • 14.01.05 - Нейрохірургія

12-05-2009

Specialized Academic Board

Д 26.557.01

The State institution "Romodanov neurosurgery institute, National academy of medical sciences of Ukraine"

Essay

Dissertation deals with the problem of improvement of diagnosis and surgical treatment for oligoastrocytomas. We investigated cases of 163 patients with OA operated in 1995-2007 in Institute of Neurosurgery, Kyiv, Ukraine. Among them women - 72, men - 91, average age was 37.4±11.4 years.Heterogeneity of OA established by hystological and genetic investigations. There were 3 groups of OA's distinguished: with prevalence of astocytic cells - 58 cases (35.6%), with oligodendroglial prevalence - 55 cases (33.7%), with astocytic and oligodendroglial as equals - 55 cases (30.7%).A lot differences in clinical course, diagnostic methods, neurosurgical treatment between OAs of different histological structure were found. The results of this research work have found application in neurosurgical practice

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