Tsygankov O. Transnasal transsphenoidal cryodestruction of pituitary adenomas

The dissertation is devoted to the problem of patients with adenomas of hy-pophysis (AH) surgical treatment results improvement using transnasal transsphenoidal selective stereotaxic cryodestruction (TTSSC) applying hard en-doscope.The dissertation is based on the results analysis of 117 pituitary tumors cases; 59 patients with AH were operated using TTSSC, 21 - using method of transnasal transsphenoidal stereotaxic cryodestruction (TTSC) (main group) and 37 - using the method of transnasal transsphenoidal microsurgical of adenomec-tomy (TTMA) (comparing group). There were 62 women and 55 men. The age of patients was from 15 to 80 years, 37,2 1,6 years in average.The analysis of obtained results shows that TTSSC was most effective at microadenomas, small pituitary tumors and also at tumors, resistible to conserva-tive therapy and in cases of intolerance to medicines prescribed. TTSC and TTMA were more effective at AH of middle and large size. It was found out that cryosurgical methods of treatment of patients with AH on 60% are less traumatic than TTMA.