Skorobogatov A. Bone tissue structure-functional condition renewal at complex treatment of tumourlike diseases and benign tumours of limb bones in children and teenagers (experimental clinical investigation).

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0409U005607

Thesis Registration Form

0409U005607.pdf

Applicant for

Skorobogatov Andrij Mykolajovych

Specialization

14.01.21 - Травматологія та ортопедія

Date of defense

09-10-2009

Specialized Academic Board

Д 11.600.04

Donetsk National Medical University

Essay

Aming at bone tissue regeneration study the experimental data have been analysed on 210 white rats and treatment results of 76 patients with tumourlike diseases and benign tumours of limb bones in the present work, applying ceramic zinc alloyed osteoаpatite for bone defect filling ostein in postoperative period. It has been experimentally proved that the above mentioned optimizes the processes of reparative bone regeneration. The transformation of regenerate tissue contant occurs faster in defect area than among animal groups without ostein. Integration processes of bone tissue are activating with graft surface, as well as the processes of ceramic osteoаpatite biodegradation. The formation of chronolized bone mineral cristal lattice and its phase contance optimization take place. Detection of structure-functional bone tissue condition verifies that there is OP among kids with FD bone lesion of upper as well as lower limbs. At KK presence - osteoаpenia of second and third degree. MDBT disturbance is more marked at upper limb bone lesions. Ceramic zinc alloyed osteoаpatite usage at bone defect plastics after removal of tumourlike diseases and benign tumour limb bones in children and teenagers is an alternative even for outobone. Ostein application in complex postoperative treatment more likely leads to improvement in some cases, even to the renewal of mineral density of bone tissue.

Thesis supervisor

Ivchenko Valeriy Konst.

Official opponents

Бруско Антон Тимофійович
Гур'єв Сергій Омельянович

Files

Скоробогатов автореф+дисс--Автореферат Скоробогатов--автореферат.doc

Скоробогатов автореф+дисс--Автореферат Скоробогатов--титул_1.doc

Скоробогатов автореф+дисс--Дисертація Скоробогатов--ВИСНОВКИ СК.doc

Скоробогатов автореф+дисс--Дисертація Скоробогатов--ВСТУП СК.doc

Скоробогатов автореф+дисс--Дисертація Скоробогатов--З М І С Т СК.doc

Скоробогатов автореф+дисс--Дисертація Скоробогатов--ПЕРЕЛІК УМОВНИХ ПОЗНАЧЕНЬ СК.doc

Скоробогатов автореф+дисс--Дисертація Скоробогатов--ПРАКТИЧНІ РЕКОМЕНДАЦІЇ.doc

Скоробогатов автореф+дисс--Дисертація Скоробогатов--РОЗДІЛ 1 СК.doc

Скоробогатов автореф+дисс--Дисертація Скоробогатов--РОЗДІЛ 2 СК.doc

Скоробогатов автореф+дисс--Дисертація Скоробогатов--РОЗДІЛ 3 СК.doc

Скоробогатов автореф+дисс--Дисертація Скоробогатов--РОЗДІЛ 4 СК.doc

Скоробогатов автореф+дисс--Дисертація Скоробогатов--РОЗДІЛ 5 СК.doc

Скоробогатов автореф+дисс--Дисертація Скоробогатов--РОЗДІЛ 6 СК.doc

Скоробогатов автореф+дисс--Дисертація Скоробогатов--СПИСОК ВИКОРИСТАНИХ ДЖЕРЕЛ СКор.doc

Скоробогатов автореф+дисс--Дисертація Скоробогатов--ТИТУЛЬНИЙ ЛИСТ ДИСЕРТАЦІЇ СК.doc

Скоробогатов автореф+дисс--Дисертація Скоробогатов--УЗАГАЛЬНЕННЯ СК.doc

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