Mishchuk O. Status of metallothioneins and the antioxidant defense system in the tissues of Anodonta cygnea L. in a polluted water enviroment

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0410U000429

Applicant for

Specialization

  • 03.00.04 - Біохімія

03-02-2010

Specialized Academic Board

Д 76.051.05

Yuriy Fedkovych Chernivtsi National University

Essay

The dissertation explores the chromatographic behavior of metallothioneins and their ability to bind ions of heavy metals in the tissues of Anodonta cygnea L. under the conditions of a polluted water . The activity of zinc-thioneins function and induction of oxidative destruction under the unfavourable environmental conditions were proved. In optimal environmental conditions were observed the induction of copper-thioneins and activation of the antioxidant defense system. The high activity and coordinated character of metallothionein response and the antioxidant defense system are proven under the conditions of low level and composition of pollution independent of seasonal specificity of these characteristics.

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