Stefanenko O. Clinical and patogenetic value of mikroelementoz in the organism of patients with system lupus erythematosus

A research object are patients with different variants of lupus; Purpose - to set clinical meaningfulness of violations of maintenance of microelements (ME) in hairs and blood of patients with lupus, to prove the pathogenic valueof microelementosis and its influence on efficiency of medical measures; Methods - clinical, X-RAY, ultrasonic, electrophisiologic, nuclear plant absorption spectrometry, biochemical, immunological, immunoenzymatic, statistical; The novelty of the results - the first set of essential and toxic ME in the hair and blood of patients with different clinical and laboratory course of lupus, we prove the pathogenetic role of changes of their contents in case of vistseritis, lymphadenopathy, lesions of the nervous system, joints, muscle and antiphospholipid syndrome, the dependence of the imbalance of the immune system and the effectiveness of the use of pathogenetic therapy of the initial state microelementosis, defined the nature of changes of individual ME in patients under the influence of treatment, established criteria for assessing the course of the pathological process and predict the effectiveness of treatment of disease; Implemented in a practice of rheumatologic department of the Donetsk Regional Clinical Territorial Medical Association, a therapeutic clinic of the Institute of Urgent and Reconstructive Surgery VK Husak of AMS of Ukraine and the Donetsk National Medical University. M. Gorky, a center of Donetsk "Biotic Medicine", as well as in the pedagogical process of Donetsk National Medical University M. Gorky; Scope of use - therapeutic and diagnostic process and therapeutic rheumatology departments, educational process of therapeutic profile of medical schools.