Shkodyak N. The biochemical profile of laboratory animal's blood under the growth of modelled inflammatory and wound processes and the application of Glycetynate

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0410U002393

Applicant for

Specialization

  • 03.00.04 - Біохімія

18-05-2010

Specialized Academic Board

Д 35 368.01

Essay

Object of research - laboratory animal's modelled inflammatory and wound processes and their treatment with application of 1% and 2% Glycetynate. The purpose of research - studying of the biochemical processes under the growth of different types of laboratory animal's outside modelled inflammatory and wound processes and the application of composite sodium containing preparations (1 and 2 per cent Glycetynate). Methods of research - clinical, gematological, biochemical (spectrophotometrical), immunological, pharmacological, toxicological, histological and statistical. Scientific novelty of work: for the first time complex research of biochemical and immunological indices in blood of laboratory animals with modelled local inflammatory and wound processes and under the application of Glycetynate were researched. The distribution of erythrocyte outside and internal Na+ and K+ ions under the Glycetynate effect at the acute modelled inflammatory process was investigated. The peculiarities of biochemical processe's course during the growth of alterative and exudative inflammation in rats were determined. The normalization of laboratory animal organism's physiological and biochemical status under the effect of Glycetynate at the outside aseptic and injected wound processes has been revealed. There were developed and ratified by State department of veterinary medicine of Ukraine technical terms "Glycetynate 1% for veterinary medicine" (TT U 24.4-00485670-044:2005) and "Glycetynate 2% for veterinary medicine" (TT U 46.15.497-2000). It is inculcated: in an educational process at the study of discipline "Veterynary surgery" and scientific researches of Lviv national university of veterinary medicine and biotechnology named after S.Z. Gzhitskiy. Field of application: veterinary medicine.

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