Zdorovtseva L. Prooxidant-antioxidant system in tissues of birds in hypo- and hyperoxia

Thesis is devoted to the support mechanisms of prooxidant-antioxidant balance in muscle and nerve tissues of geese in hypo- and hyperoxia. Established specificity of the system of antioxidant protection in morphologically muscle tissues of geese that are characterized by varying levels of oxygen consumption under conditions of hypo- and Oxygenation during the transition from embryogenesis to postnatal period. Proved that the character of AOP muscle tissue depends on the level of oxygen consumption by these tissues. Among the investigated muscle tissue biggest impact in hypo- and Oxygenation exposed myocardium. The formation of adaptive response to oxidative stress in cardiac muscle is due to activation of GAP, and resources of vitamin E and ?-carotene. Simultaneously, the ability of myocardium to lipid peroxidation GSH decrease the unsaturation of fatty acids. Was approved a new approach to the assessment of balance POL ? AOA in terms of consistency indices. Established that the activation of brain tissues in late embryogenesis AOP is through additional enhanced coherence between indicators of prooxidant-antioxidant balance. It was proved that support equilibrium AOA ? LPO in brain tissues during the transition to post-natal existence is also run by neurohormonal processes that reduce lipid unsaturation LCD brain and contribute less vulnerable AFC spatial modification of lipid bilayer of cell membranes. Shows the degree of intensification of LPO in heart and brain tissues against vitamin A deficiency proved a stabilizing role of increased output and vitamin A provision in the state of prooxidant-antioxidant balance in heart and brain tissues of birds in hypo- and Oxygenation.