Goncharenko O. The biochemical mechanisms of the effect of manganese chloride loading dose on the cellular metabolism in organs and tissues of white rats

Object of research: the dynamics of the content of macro-and micronutrients, state of cellular and subcellular membranes, the activity of lipid peroxidation in the tissues of white rats in condition of incresing of manganese. The target of inverstigation: studying the mechanisms of action of sublethal doses of manganese chloride on cell's metabolism in the tested samples. Methods of inverstigation: methods of acute model experiment about the effect of load MnCl2, atomic-absorption spectrometry, biochemical and polarographic methods, methods of mathematical analysis. Theoretical and practical results and novelty: for the first time is made the experimental study about the influence of sublethal loads of manganese chloride on cell metabolism in tissues and organs of white rats. Results of the styding are inculcatad into lectures and prastical work of special education courses in Kharkiv National Pedagogical University of G.S. Skovoroda and Kharkiv State Academy of Physical Culture.