Zarivna N. Development and standardization of mucolytic drugs with dense wild thyme extracts and thyme essential oil in capsules

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0413U007242

Applicant for

Specialization

  • 15.00.03 - Стандартизація та організація виробництва лікарських засобів

22-11-2013

Specialized Academic Board

Д 64.605.01

National University of Pharmacy

Essay

The work is dedicated to the development and standardization of mucolytic drugs with a thick extract of thyme and creeping thyme essential oil in capsules. A phytochemical study of grass creeping thyme. The technology of liquid extract creeping thyme which is gradient extraction using different alcohol strength ( 60 % and 30% (v / v )) and hot water. The optimal conditions for thick creeping thyme extract and selected as a quantitative measure flavonoid content of at least 2.5% in terms of apigenin . With the help of variance and regression analyzes developed the best of technology and capsules with thick creeping thyme extract and essential oil of thyme usual. The methods of standardization developed capsules investigated their stability.

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