The object of study: the processes of regulation of inter-regional differentiation of consumer prices in Ukraine. The goal: improving the theoretical and methodological foundations and developing of practical recommendations for improving the regulation of inter-regional differentiation of prices for consumer goods. Methods: theoretical generalization, analysis, synthesis, deduction, classification, statistical analysis, clustering, comparison, econometric analysis, economic and mathematical modeling. The novelty: the first time proposed the mechanism of regulation of inter-regional differentiation of consumer prices that includes tools of impact for smoothing of regional price disparities, particularly in the field of state regulation of prices for consumer goods, regional socio-economic disparities, creating conditions for the effective functioning of the consumer market, improved interpretation of the essence of the concept of "interregional differentiation of prices", which is a type of spatial price differentiation and is regarded as the difference in prices when selling similar goods (works, services) in different regions within the same country, and also acts as indicator of spatial economic equilibrium, integration and balance of the internal market, the intensity of inter-regional production and trade relations and, simultaneously, the result of social and economic policy and effectiveness of functioning the consumer market, system of areas of price regulation on the consumer goods market in the context of solving the problems of pricing, classification of factors interregional differentiation of prices for consumer goods by features of the territorial scope and areas of influence. Scope: in activities of the Agrarian Exchange under the Cabinet of Ministers of Ukraine for infrastructure development of the consumer market for promoting inter-regional exchange of goods, the Committee on Industrial and Regulatory Policy and Entrepreneurship of the Supreme Council of Ukraine for reducing inter-regional price differentiation, the State Inspectorate for Control over Prices in Lviv region for improvement of monitoring the consumer goods market and its institutional maintenance, LLC "Furniture Factory VEEM" for reducing the number of middlemen in the marketing of products and the setting up of regional cooperation.