Khromylova O. Development of technology and standardizations of pills is on the basis of of izoniazida with tiotriazolinum

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0415U005655

Applicant for

Specialization

  • 15.00.03 - Стандартизація та організація виробництва лікарських засобів

02-10-2015

Specialized Academic Board

Д 64.605.01

National University of Pharmacy

Essay

The dissertation is devoted to the development and standardization of new combined tableted medicament for the treatment of tuberculosis including isoniazid and thiotriazolin. On the basis of physico-chemical, technological and pharmacological properties of drug substances using the methods of mathematical design of experiments, composition and technology of tablets with isoniazid and thiotriazoline by wet granulation and direct compression method was designed. Correct methods for standardization of active ingredients, on which the quality control methods were drafted, were created for development of medicamnet "Triotiazid".

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