Уarovenko L. Age features of the liver’s injury and regeneration in rats with chronic alcohol intoxication, the ways of those disorders correction

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0416U003772

Thesis Registration Form

0416U003772.pdf

Applicant for

Specialization

  • 03.00.04 - Біохімія

30-06-2016

Specialized Academic Board

К 58.601.04

I. Horbachevsky Ternopil State Medical University

Essay

The thesis is devoted to study age – features of liver tissue regeneration on a background of chronic alcohol intoxication and after correction by quercetin and glutargin. On the background of the chronic alcoholic liver damage marked quantitative increase of cytolysis and cholestasis syndrome data and liver dysfunctions in immature and old rats. An increase of nuclear DNA fragmentation with inhibition of synthetic processes in hepatocyte nuclei and polyploidization are marked at all animals. Glutargin decreases symptoms of cholestasis and cytolysis, quercetin increase protein synthetic function of liver and improves liver regeneration.

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Files

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dіs.doc.doc

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