Yefimenko N. NO-dependent regulation of the morphofunctional state of platelets and erythrocytes of blood under alcohol intoxication

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0417U003536

Thesis Registration Form

0417U003536.pdf

Applicant for

Specialization

  • 03.00.04 - Біохімія

23-06-2017

Specialized Academic Board

К35.051.14

Essay

The development of oxidative and nitrosative stress under the studied pathology is the main cause of the change in structural and functional state of platelets and erythrocytes. Strengthening of free-radical processes causes the development of oxidative stress in blood cells under alcoholic intoxication (AI). NO overproduction by inducible NO-synthase and increase of its pool due to nitrite reductase activity of deoxyhemoglobin under AI leads to a switching of NO function from physiological regulatory to cytotoxic one.

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Files

aref.doc

dis.doc

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