Katriy T. Hemostasis system of the patients with ischemic stroke at the different stages of the disease

The comprehensive study of the hemostasis system of the patients with the different subtypes of ischemic stroke during the acute phase as well as 1 year past acute phase was carried out. The influence of nonspecific protein factors on the key parameters of the hemostasis system was investigated. The concentration of the SFMC in the plasma of patients past 1 year of acute AIS was 8 times higher and 1 year past CIS was 14 times higher than in healthy condition. Рast 1 year of both subtypes of ischemic stroke, the extension of the eugrobulins lysis time and the Hageman-dependent fibrinolysis were showed. According to the level of vWf 1 year past ischemic attack only 38 % of patients with atherothrombotic stroke had a factor level on 50 % higher than norm. But 40 % of patients with CIS level of vWf was increased an average on 75 %. Elevated levels of TPA and PAI-1 by 30% were observed.