Dukkart K. Information technology of the analysis of changes in single-channel electrocardiogram indicators in different states of the human body

An important scientific and practical task of improving the methods for analyzing the functional state of the cardiovascular system on the basis of the evaluation of "subtle" changes in the shape of fragments of a single-channel electrocardiogram in various states of the body is solved in the thesis. The basis of information technology is made up of new methods that realize the development of the ideas of phasegraphy in conditions of assessing the electrocardiogram under the load with qualitative and quantitative analysis of regulatory patterns and cognitive computer graphics, and also number of traditional and modified methods for computing the chaoticness of biomedical signals are proposed. For the first time, a method for determining the area of the entropy phase portrait calculated in sliding windows is presented, which provides important information on the subtle changes in the ECG signal caused by external influences on the human body. The developed information technology for user decision-making support integrates program modules realizing the developed methods. Based on the processing of real data, the informative nature of the developed methods is justified, studies are carried out in clinical practice, in particular, with surgical intervention (coronary artery bypass grafting and stenting), drug treatment and stress tests.