Pylypchuk T. Features of bone tissue metabolism in case of experimental crush-syndrome

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0421U101103

Thesis Registration Form

0421U101103.pdf

Applicant for

Specialization

  • 03.00.04 - Біохімія

19-04-2021

Specialized Academic Board

К 58.601.04

Ternopil National Medical University named after I. Gorbachevsky of the Ministry of Health of Ukraine

Essay

The dissertation is devoted to the study of the metabolic disorders features, macro- and microelement composition and bone tissue structure in rats with modelled crush-syndrome. The post-compression period of the experimental crush-syndrome is accompanied by an increase in endogenous intoxication, free radical oxidation processes and a decrease in oxidative energy supply, which subsequently induces cell death. Reduced bone formation and increased bone resorption, which are accompanied by catabolism of connective tissue have been established. The maximum changes were determined on the 14th day of observation. In addition, the development of dysmacro- and dysmicroelementosis, both in the femur and in the blood and liver of rats at different times of the crush-syndrome post-compression period was found.

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Files

autoreferat-aref.doc

Дисертація Пилипчука Т.П..doc

Дисертація Пилипчука Т.П..doc

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