Serebryanyk O. Ribosomal ATPase from higher eukaryotes

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0499U000184

Applicant for

Specialization

  • 03.00.03 - Молекулярна біологія

25-05-1999

Specialized Academic Board

Д26.237.01

Essay

It has been first shown that highly purified ribosomes from higher eukaryotes are strongly associated with ATPase activity, and its properties have been studied. Two active sites have been revealed, one of them may be stimulated by aminoacyl-tRNA. The data obtained show participation of the ATPase in the regulation of the ribosomal A-site responsible for the selection of cognate tRNA. A comparative analysis of the ribosomal ATPase and yeast EF-3 has elucidated some common properties.

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