Gerush I. The state of the oxidant and antioxidant systems of the organism under normal and experimental pathological conditions after the influence of the spirituous tincture of Echinacea purpurea

Biochemical mechanisms of the action of Echinacea purpurea tincture on the state of the oxidant and antioxidant systems of the organism under normal and experimental pathological condi- tion (erosive-ulcerous injury of the gastroduodenal zone and toxic hepatitis) were substantiated in the thesis. The action of the prepa- ration was aimed at normalization of the activity of enzymes of organism's antiperoxide protection and stabilization of cellular membranes. It has been established that Echinacea purpurea tincture can effectively inhibit radiation-induced processes of lipid peroxidation and its usage causes a positive corrective effect as to the basic indices of the antioxidant system. The biologic effective- ness of the preparation in the destruction of peroxidation products and their toxic metabolites, the stabilization of the organism's antioxidant system state has been caused by biologically active substances in its composition