Grygorenko O. 3. Prognostic role of doplerechocardiography in the detection of cardiovascular impairments in patients with rheumatoid arthritis

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0499U001930

Thesis Registration Form

0499U001930.pdf

Applicant for

Specialization

  • 14.01.12 - Ревматологія

22-06-1999

Specialized Academic Board

Д 26.616.01

State Institution National Scientific Center "The M.D. Strazhesko Institute of Cardiology National Academy of Medical Sciences of Ukraine"

Essay

3. Patient (100) for rheumatoid arthritis. The questions of heart impairments revealed during clinical сomplex dоplerechocardiographic (DEchoCG)examination of patients with rheumatoid arthritis, and the influence of nonsteroid anti-inflammatory preparation diclofenac on the functional state of the heart. DEchoCG with colour scanning enabled to reveal: diastolic dysfunction as a preclinical sign of cardiac insufficiency and a marker of insidious ischemia - in 49% of patients with RA; negative changes of contractive function as a manifestation of autoimmune inflammation - in 27%. of patients; and regurgitations in the valves with (or without) fibrotic impairment in 41% of patients. Any reliable changes in the functional state of heart were not revealed after two-week treatment with diclofenac Recommendations addressed to the medical specialists at rheumatology departments.

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