Kolesnichenko V. Vertebral osteochondropathy. Early diagnosis and prognosing of the disease course.

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0501U000175

Applicant for

Specialization

  • 14.01.21 - Травматологія та ортопедія

24-04-2001

Specialized Academic Board

Д.26.606.01

Essay

250 patients with vertebral osteochondropathy. Aim: elaboration and verification of the pathogeny's conception of the osteochondropathy (on the basis of study of the evolution of structural and functional changes of vertebral segments with disease different variants) with further definition criterious of the early diagnostics and prognosing. Clinical, radiological (roentgenometric, radiopaque, non-invasive - JMR-tomograph Picker Norton (0,1T), densitometry (вone densitometr NK 364), biochemical, morphological, statistic methods. The new direction in studyng the pathogenesis of osteochondropathy have been worked, and according to this direction the disease repre-sents the continuous displastic-dystrophic process; and its essential is the structural anomaly of the vertebral body end-plates. For the first time the early qualitative and quantitative clinical and radiology sings at different local-ization have been found out, as well as aging dynamics of the structural-functional changes of the disease var ious forms have been study. The calculating tables for the differentation of the osteochondropathy early manifestations of various localization as well as permit to prognosticate the clinical course and the outcomes at the disease differ-ent variants have been worked up. Research resalts are used in IVJP named after M.I. Sytenko of Ucrainian MSA, ITO of Ucrainian MSA, Russian's CITO, Kiev's, Kharkov's, Dnepropetrovsck's,Nyckolaev's, Odessa's, Lvov's, Sympheropol's, Moscow's orthopaedics-traumatology clinics ; studying at the orthopaedics-traumatology departments of the KhADE, Kharkov's, Odessa's, Krim's medical institutes, Dnepropetrovsck's medical academy, Russian's university of friendship people. Traumatology and orthopedics.

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