Volos L. Prion-associated spongiforme encephalopathy Creutzfeldt-Jacob: quantitative morphological diagnostics

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0504U000477

Applicant for

Specialization

  • 14.03.02 - Патологічна анатомія

16-09-2004

Specialized Academic Board

Д 26.003.06

Bogomolets National Medical University, Ministry of Health of Ukraine

Essay

Is established that a criterion prion-associated spongiforme encephalopathy Creutzfeldt-Jacob is the population of morphological indications: loss of neurons, spongiosis, gliosis, presence prion-associated (PrP-Sc) deposits in saved neurons, astroglia, plakes, walls of vessels and spongiforme vacuoles in cortex and subcortex structures, hippocampus and cerebellum at a lack of immune responses, acute and chronic inflammation. Represented priority datas of quantitative morphological diagnostics.

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