Kucherenko L. Development of technology and standardization of tableted drugs on the basis of 1,2,4-triazole derivatives

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0510U000155

Thesis Registration Form

0510U000155.pdf

Applicant for

Kucherenko Lyudmila Ivanovna

Specialization

15.00.03 - Стандартизація та організація виробництва лікарських засобів

Date of defense

16-02-2010

Specialized Academic Board

Д 64.817.01

Essay

The dissertation is devoted to the creation of three novel drugs: new original preparation bromide 1-?-phenylethyl-4-(n-dimethyl-aminobenzylidenamino)-1,2,4-triazole, proprietary name is Cardiotril; two new combined fixed preparations Thiodarone (Amiodarone hydrochloride with Thiotriazoline) and Indotril (Indomethacin with Thiotriazoline). Determined pharmacokinetic parameters of Cardiotril and Thiodarone tablets show their high bioavailability

Thesis supervisor

Groshevoj Taras Andreyevich

Official opponents

Гризодуб Олександр Іванович
Дмитрієвський Дмитро Іванович
Петюнін Геннадій Павлович

Files

Автореферат_Кучеренко.doc

Диссертация_Кучеренко.doc

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