Garna S. Development and standardization of the technology of complex processing of plant raw material

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0512U000543

Applicant for

Specialization

  • 15.00.03 - Стандартизація та організація виробництва лікарських засобів

14-06-2012

Specialized Academic Board

Д 64.605.01

National University of Pharmacy

Essay

For the first time in Ukraine systematic research on the development of methodological approaches to the complex processing of medicinal herbs have been conducted. The features and optimal conditions for extraction of biologically active substances from plant raw material with lipophylic or hydrophylic properties have been determined depending on their physico-chemical properties, the nature of the solvent and preparation of plant raw material. A monographs SPU "Blueberry fruits dry", "Blueberry fruits fresh" has been draft. For the first standardized technologies of complex processing of plant raw material in phytochemical manufacturing have been theoretically justified, formulated and experimentally confirmed. A perspective of extracted meal after obtaining the target product has been shown as prospective fitosubstances with different pharmacological properties, as excipients in pharmaceutical manufacturing, as special food products for human and animal. Prospective hypolipidemic preparation "Likopersykol" has been proposed and its technology has been elaborated due to pharmacological data. An original sedative agent "Sedavit, solution" has been developed and implemented into industrial production.

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