Vovchuk I. Age-related features of regulation of the system of proteolysis at a tumor process in the endometrium and ovarian.

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0513U000185

Applicant for

Specialization

  • 03.00.04 - Біохімія

11-02-2013

Specialized Academic Board

Д 76.051.05

Yuriy Fedkovych Chernivtsi National University

Essay

Increased malignancy in the endometrium and ovarian was accompanied with changes in physico-chemical, biochemical and regulatory properties of carboxypeptidase A, which is represented by multiple forms. First, we showed that ovarian carboxypeptidase A has a greater affinity for carbobenzoxyglutamylphenylalanine than endometrium carboxypeptidase A, and tumor enhancement is associated with an increased affinity tumor enzymes of endometrial and ovarian to the substrate.

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