Yelisyeyeva O. Mechanisms of fatty acid and hypoxic stimulation of oxygen-dependent processes during formation of adaptive reactions

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0514U000302

Applicant for

Specialization

  • 03.00.04 - Біохімія

28-04-2014

Specialized Academic Board

Д 26.001.24

Taras Shevchenko National University of Kyiv

Essay

The dissertation is dedicated to the study of the mechanisms involved in the development of stress protective adaptive reaction of activation through mild stimulation of the oxygen-dependent reactions by fatty acids (Amaranth oil) and hypoxia (sessions of interval hypoxia) based on the molecular, cellular and organ levels of organization. For the first time, it was demonstrated that increase in the heart rate variability (HRV), which is attributed to mild activation of free radical (FR) reactions, more intense fluctuation of reactive oxygen species (ROS) and production of endogenous oxygen, is based on the transition of the mitochondria to the active metabolic state, increase in the stability and functional activity of the plasmatic membranes.

Files

Similar theses