Vladymyrova I. Standardization of approaches to targeted search of herbal medicines for the treatment of thyroid gland

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0514U000405

Applicant for

Specialization

  • 15.00.03 - Стандартизація та організація виробництва лікарських засобів

06-06-2014

Specialized Academic Board

Д 64.605.01

National University of Pharmacy

Essay

The thesis is devoted to the development of contemporary approaches to targeted search of medicinal plants and developed based on these drugs for the prevention and treatment of thyroid algorithms targeted search facilities of plant origin for the prevention and treatment of thyroid disease groups. On the basis of experimental studies suggested features and principles of using in diseases of the thyroid gland and the correlation ratio "structure-activity" between compounds containing iodine and thyroid hormone levels. Systematic comparative study of organic and inorganic iodine-containing compounds in Laminaria thallies. The method of quantitative determination of organic iodine compounds by HPLC in Laminaria thallies and set its validation data. Theoretically grounded formulated and experimentally verified way to complex processing of raw Laminaria thallies obtaining credit thyroid stimulating action «Iodolaminum» and «Iodolaminum+» and antiviral action «Oligovir». A monograph SPU 1.3 «Kelp» SPU 1.4 «Laminaria thallies» project SPU monograph «Iceland moss»; newsletters about innovations in health care. Developed dietary supplement «Thyreophyt».

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