The object of investigation - a traumatic process in HIV-infected patients with multiple injuries; purpose of the study - to improve the survival of HIV-infected patients with multiple injuries in the prehospital and early hospital stages of health care through the establishment of science-based system of measures aimed at addressing and reducing the impact of causal factors of fatal traumatic process flow; methods - clinical, clinical, laboratory, enzyme immunoassay, immunological, microbiological, medical nonparametric statistics; novelty and results - defined clinical and epidemiological characteristics of traumatic process and clinical and nosological characterization of lesions in HIV-infected patients with multiple injuries, a comparative clinical characteristics of current traumatic process in HIV-infected patients with multiple injuries and patients with missing immunosuppression, analyzed the incidence of the syndrome multiple organ dysfunction / multiple organ dysfunction syndrome in HIV-infected patients with multiple injuries, set the structure of infectious complications among HIV-infected survivors and their influence on the course of the traumatic process in this category of patients, investigated the main damage mechanism of the biological target toxins whole plasma in the development of traumatic disease in HIV positive victims and its comparison with that on the victims without immunosuppression, examine and evaluate the role of risk factors for mortality trends traumatic process among HIV-infected patients with polysystemic injuries, first established the nature and characteristics of the immune response to trauma in HIV-infected patients with multiple injuries using the acute phase proteins, pro-inflammatory (TNF-?) and anti-inflammatory cytokines (IL-10), is scientifically proved, developed and established a system of measures to increase survival among HIV-infected patients with multiple injuries; implemented - in the educational process at the Department of Traumatology and Orthopedics of Lviv National Medical University, the Department of Disaster Medicine of the National Medical Academy of Postgraduate Education, the Department of traumatology, orthopedics and field surgery of Ternopil State Medical University, in the diagnostic and treatment process at the Ukrainian scientific-practical center of emergency medical care and disaster medicine of the Ministry of Health of Ukraine, the Department of Traumatology of Kharkiv Regional Clinical Hospital - Center for emergency medical care and disaster medicine, department of polytrauma of Kyiv city clinical emergency hospital, department of Traumatology and orthopedics of Vinnitsa city emergency hospital, department of Traumatology and orthopedics of Kyiv regional clinical hospital, department of Traumatology of Zhytomyr city hospital N2, field of application - medical-diagnostic process of specialized trauma hospital medical institutions, centers of emergency medical care, research and teaching processes traumatological departments of medical schools.
