Ferenchuk Y. State of energy metabolism and hydrogen sulfide metabolism system under conditions of experimental nephropathy and influence of glutathione

Українська версія

Thesis for the degree of Doctor of Philosophy (PhD)

State registration number

0820U100491

Thesis Registration Form

0820U100491.pdf

Applicant for

Specialization

  • 091 - Біологія. Біологія

27-11-2020

Specialized Academic Board

ДФ 76.600.005

HSEE of Ukraine "Bukovinian State Medical University"

Essay

Kidney disease often leads to the general state of oxidative stress and can co exist with different liver diseases, or stimulate their development. The qualifying paper studies indicators of the state of energy metabolism, oxidative-antioxidant system, and hydrogen sulfide metabolism in the liver and blood of rats under conditions of the physiological norm, nephropathy, and influence of exogenous glutathione. This study amplifies the theoretical data on the mechanisms of antioxidant and hepatoprotective action of glutathione and its ability to regulate ATP and hydrogen sulfide formation. The received results regarding the effect of glutathione on the state of energy metabolism, the oxidative-antioxidant system, and the hydrogen sulfide exchange system by kidney disease can be the theoretical basis for further study of the possibility to use glutathione for nephro- and hepatoprotective effects by kidney disease.

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Files

autoreferat-Анотація _дисертації _Ференчук.pdf

dissert_Ferenchuk_Yelena.pdf

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